COVID-19 Bivalent Booster Effectiveness against Severe Disease

The CDC Morbidity and Mortality Weekly Report (MMWR) released two new studies showing COVID-19 bivalent booster effectiveness against severe COVID-19 disease. The studies showed:

• The bivalent booster offered additional protection against COVID-19 associated hospitalizations to people who had only received monovalent vaccines (≥2 doses).
• The bivalent booster offered additional protection against severe disease compared to people who had only received monovalent vaccines (≥2 doses).

MMWR Studies:

• Early Estimates of Bivalent mRNA Vaccine Effectiveness in Preventing COVID-19–Associated Hospitalization Among Immunocompetent Adults Aged ≥65 Years
  
• Early Estimates of Bivalent mRNA Vaccine Effectiveness in Preventing COVID-19–Associated Emergency Department or Urgent Care Encounters and Hospitalizations Among Immunocompetent Adults

myCAvax Updates

Pfizer and Moderna Bivalent Vaccine

CDPH has received a small additional allocation of the Infant/Toddler Bivalent vaccines to support provider orders. In addition, routine allocation refreshes of Pediatric and Adult Bivalent products will be available today, December 23.

Reminder: Holiday Ordering Calendar

The December 2022 and January 2023 Holiday Ordering and Delivery Cadence Calendar is available on EZIZ.

Reporting Vaccine Administration Errors

1. Inform the recipient of the vaccine administration error.
2. Refer to CDC’s Interim Clinical Considerations (Appendix D) to determine whether revaccination may be recommended. Contact the manufacturer for any questions: Janssen: 1-800-Janssen (1-800-526-7736) | Moderna: 1-866-MODERNA (1-866-663-3762) | Novavax: 844-NOVAVAX | Pfizer-BioNTech: 800-438-1985
3. Contact your local CAIR2/RIDE Representative to determine how the dose should be entered into the CAIR, both as an administered dose and to account for inventory.
4. Report all COVID-19 vaccine administration errors to VAERS - even those not associated with an adverse event. (Reporting to VERP is strongly encouraged to help prevent future errors or patient harm.)
5. Determine how the error occurred and implement strategies (e.g., education/training) to prevent it from happening again.

See Preventing Administration Errors for guidance by error type.

For detailed guidance, reference the Provider Operations Manual. 

Vaccine Expiration Dates 

Pfizer and Moderna products have received shelf-life extensions. Please continue to check the expiration dates of your vaccines:

• Pfizer Expiry Checker
• Moderna Expiry Checker

CDPH expects all J&J vaccine to expire by February. If you still have J&J in stock, pay attention to the upcoming expiration dates:

• J&J Expiry Checker

Reminder: Upcoming Holiday Webinar Cancellations

CDPH COVID-19 webinars are cancelled on the following dates:

Monday My Turn and myCAvax Office Hours:

Monday, December 26, 2022

Friday Provider Webinar:

Friday, December 30, 2022 

The myCAvax Team Appreciates Your Feedback!

The myCAvax team is always looking for feedback on how to better improve the myCAvax experience. If you have feedback or suggestions for future improvements, please complete the survey here.